Presented by Dr. Robin Bogner, PhD Associate Professor of Pharmaceutics at the University of Connecticut…
Webinar Category: Freeze-Drying
Freeze-Drying COVID-19 Diagnostics: Formulation & Process Development and Lyophilizer Selection
Reagents typically used in diagnostic test kits for diseases such as COVID-19 tend to contain reactive components such as enzymes or antibodies, which can be challenging to stabilize for commercial
Overcoming Long Reconstitution Times
Rapid reconstitution is an important attribute for lyophilized drug products. However, a major challenge to the development of high concentration lyophilized protein formulations is slow and variab
Anomalous Behavior of Mannitol Hemihydrate: Implications on Sucrose Crystallization in Colyophilized Systems
Mannitol, a popular bulking agent, has propensity to exist in different physical forms in the lyophilized formulations. Presence of mannitol in its hydrated form is generally undesirable as the rel
Mythbusting Ten Lyo Misconceptions (Part 1)
There are many misconceptions in lyophilization, most of which have arisen due to the complex interaction between formulation, process, equipment and the requirements of the final product, and that
Mythbusting Ten Lyo Misconceptions (Part 2)
There are many misconceptions in lyophilization, most of which have arisen due to the complex interaction between formulation, process, equipment and the requirements of the final product, and that
Impact of Freeze-Drying Process and Lyoprotectants on Nanoparticle Stability
Freeze-drying is an effective approach to improve the storage stability of nanomedicines. The optimal freeze-drying process and lyoprotectants for three types of nanoparticles: solid lipid nanopart
Next-Generation Process Monitoring in Lyophilization – Applications for Wireless Sensor Technology
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Software Tools for Pharmaceutical Lyophilization Process Development
Physical Sciences Inc., in collaboration with the University of Connecticut, the University of Massachusetts Lowell, Purdue University, Genentech and Merck, has developed software modeling tools fo
Interplay of Formulation Components on Excipient Functionality During Lyophilization
Lyophilization (or freeze-drying) finds extensive application in the development of injectable pharmaceutical proteins. However, this process has a potential to destabilize proteins due to stresses