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Distribution of vaccines requiring cold storage is costly and complex. This webinar presents the development of a lyophilized simian adenovirus-vectored vaccine (ChAdOx1 platform) enabling ambient
Join us for a deep dive into efficient peptide purification workflows for pharmaceutical applications. This webinar explores how Prep HPLC and flash chromatography can be seamlessly integrated with
Design of freeze-drying processes is often approached with a “trial and error” procedure when scientists are new to the subject. In some cases, the freeze-drying recipe used in the first labora
Product temperature measurement is the key to optimizing lyo cycles, working within the design space and conquering scale-up challenges. The most common method, using standard Type T Thermocouples,
Presented by Dr. J. Jeff Schwegman, PhD, CEO of Labyrinth Biopharma…
Presented by Dr. J. Jeff Schwegman, PhD, CEO of Labyrinth Biopharma…
Lyophilization Basics: An Introduction to Freeze-Drying (Part 1 of 4) covers: Presented by Dr. J. Jeff Schwegman, PhD, CEO of Labyrinth Biopharma…
Surfactants are widely used in frozen and freeze-dried protein formulations to prevent ice-surface-induced destabilization. Polysorbates (PS), especially PS20 and 80, are commonly used in protein p
Mannitol is a popular excipient in lyophilized injectable small and large molecule formulations. Mannitol crystallizes readily in aqueous solutions enabling primary drying at elevated temperature,
When prelyophilization solutions are frozen, selective crystallization of a buffer component is known to cause a pH shift, which can sometimes be pronounced. Such pH shifts have been reported with
