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Hull LyoConstellation® Production Lyophilizers
Hull LyoConstellation® Production Lyophilizers
Hull LyoConstellation® Production Lyophilizers
If you need a lyophilizer that slots into your fill-finish workflow and is clean room ready, Hull LyoConstellation® S10, S20, S30, S80, S100, and S130 Production Lyophilizers are here to help.
LyoConstellation production lyophilizers build on SP’s reputation as a pioneer of freeze-drying technologies. Ready-to-order, and equipped and controlled as a production system, the LyoConstellation offers a seamless approach to scale-up while being designed for line integration. And, with our comprehensive and innovative range of Line of Sight™ Lyophilization and PAT Tools for your high-value products, we’ve done the hard work, so you don’t have to.
Features & Benefits
- Taking you from start to finish — ideal for cycle development and scale-up to stability, pilot, and clinical batch production, through full aseptic production
- Technologies that ensure quality — full suite of PAT tools and technologies enables Line of Sight approach in cycle development and scale-up for simplified technology transfer, assuring product safety and quality in production
- Validation made easy — validation ports in chamber and condenser as standard, with full documentation package and support available
- Accurate end points — Pirani gauge and capacitance manometer as standard
- Full Steam in Place (SIP) & Clean in Place (CIP) execution, with manual/H2O2 option
- Isolator ready with auto locking doors
Line of Sight™ Lyophilization & PAT Tools
To help you overcome the mounting challenges when scaling up your lyophilization processes, LyoConstellation® production lyophilizers are compatible with our state-of-the-art Line of Sight™ Lyophilization and Process Analytical Technologies (PAT) suite of scalable tools:
- LyoFlux® TDLAS — measure water vapor mass flow with accuracy during freeze-drying
- SMART™ Freeze Dryer Technology — get instant feedback on important product data including resistance, heat flow, and mass transfer
- TEMPRIS® Wireless Sensors — advanced wireless temperature monitoring for the highest quality product, on budget and on time
- ControLyo® Nucleation Technology — take control of your freeze-drying with cutting-edge nucleation technology for precise control of the freezing point
Applications
Specifications
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Condenser Surface Area (S10/20/30)0.85, 1.85, or 3.48 m²
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Condenser Capacity (S80/100/130)80, 150, or 200 L
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Lowest Condenser Temperature-65 °C
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Shelf Temperature Control Range-55 °C to 65 °C
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Number of Shelves5, 6, 8, 9, 10, or 13 (1 radiant each)
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Materials316L stainless steel
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Dimensions (W x D x H)variable
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Weightvariable
Resources
- Hull LyoConstellation® Production Lyophilizers
- Hull LyoConstellation® S10 — Spec Sheet
- Hull LyoConstellation® S20 — Spec Sheet
- Hull LyoConstellation® S30 — Spec Sheet
- Hull LyoConstellation® S80 — Spec Sheet
- Hull LyoConstellation® S100 — Spec Sheet
- Hull LyoConstellation® S130 — Spec Sheet
- Putting Fill-Finish Customization into Your Line of Sight — White Paper
- Technologies & PAT Tools to Overcome LyoChallenges — White Paper
