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Hull LyoConstellation™ S80/S100/S130 Production Lyophilizers
Hull LyoConstellation™ S80/S100/S130 Production Lyophilizers
Hull LyoConstellation™ S80/S100/S130 Production Lyophilizers
If you need a lyophilizer that slots into your fill-finish workflow and is cleanroom ready, the Hull LyoConstellation™ pilot lyophilizers are here to help. With a comprehensive range of innovative technologies for your high-value products — including controlled ice nucleation, fluid condenser cooling, and large diameter vapor ports for high flow — we’ve done the hard work, so you don’t have to.
- Flexible — models include S80, S100, and S130 to ensure you get the lyophilizer you need
- Scalable — utilizes the same software and technology options as smaller systems
Overview
Our Hull LyoConstellation™ S80, S100 and S130 Production Lyophilizers build on SP’s reputation as a pioneer of freeze-drying technologies. Equipped and controlled as a production system, the LyoConstellation offers a seamless approach to scale-up while being designed for line integration. If time is not on your side, rest assured that our lyophilizers are ready to order — for faster than average market delivery.
And, to help you overcome the mounting challenges when scaling up your lyophilization processes, LyoConstellation lyophilizers are compatible with our state-of-the-art Line of Sight™ Process Analytical Technologies (PAT) suite of scalable tools:
- LyoFlux® TDLAS — measure water vapor mass flow with accuracy during freeze-drying
- SMART™ Freeze Dryer Technology — get instant feedback on important product data including resistance, heat flow, and mass transfer
- TEMPRIS® Wireless Sensors — advanced wireless temperature monitoring for the highest quality product, on budget and on time
- ControLyo® Nucleation Technology — take control of your freeze-drying with cutting-edge nucleation technology for precise control of the freezing point
Features & Benefits
- Taking you from start to finish — ideal for cycle development and scale-up to stability, pilot and clinical batch production, through full aseptic production
- Technologies that ensure quality — full suite of PAT tools and technologies enables Line of Sight approach in cycle development and scale-up for simplified technology transfer, assuring product safety and quality in production
- Validation made easy — validation ports in chamber and condenser as standard, with full documentation package and support available
- Accurate end points — Pirani gauge and capacitance manometer as standard
- Built for demanding lyophilization needs — each of our units can accommodate vials up to 100 mL, so you can develop the most aggressive of freeze-drying cycles safe in the knowledge that you’re using a lyophilizer that works with you
- Full Steam in Place (SIP) & Clean in Place (CIP) execution, with manual/H2O2 option
- Isolator ready with auto locking doors
