Evaporation

Penicillin, the first antibiotic, was discovered over 90 years ago and revolutionized medical potential. Before the advent of antibiotics, bacterial infections were a leading cause of death and the

Proteolysis Targeting Chimeras (PROTACs) were first conceptualized around 20 years ago and are transforming drug discovery. Before PROTACs, many disease-causing proteins were considered “undrugga

High-performance liquid chromatography (HPLC) is a critical analytical technique for assessing oligonucleotide purity, yet conventional sample-preparation steps can create significant bottlenecks i

As COVID-19 testing volumes expanded worldwide, maintaining consistency, throughput, and analytical confidence in oligonucleotide production became increasingly complex….

The emergence of COVID-19 generated an immediate global requirement for large quantities of high-performance oligonucleotides to support RT-qPCR diagnostic testing….

Controlled crystallization is essential in identifying and stabilizing polymorphic forms of active pharmaceutical ingredients….

To enhance the sensitivity and reproducibility of LCMSMS drug screening in forensic casework, Forensic Science Ireland evaluated the Genevac EZ-2 system as an alternative to nitrogen blow-down evap

Residual solvent vapors can create hazardous and unpleasant odors upon completion of evaporation runs, even when condensers capture the bulk of vapors….

Hair analysis provides a retrospective record of drug or alcohol use over extended periods, but sample volatility and contamination can compromise data reliability….

Leochimica Laboratories were founded in 1980, and are at the cutting edge of research into newmethods for environmental analysis. Working in a range of areas under the heading of Environmental An

Analysts at Great Lakes Polymer Additives employed centrifugal evaporation to enhance safety and efficiency in competitive product de-formulation. Using the Genevac EZ-2 system, solvent removal fro

Metabolite profiling plays a crucial role in understanding drug metabolism and toxicity, but analytical accuracy can be compromised by errors introduced during sample preparation…

High-throughput compound purification requires efficient sample tracking and solvent removal to maintain process integrity. This paper examines approaches for integrating preparative HPLC with evap

Mixtures containing both volatile and high-boiling-point solvents, such as methanol/DMSO systems, pose difficulties for controlled evaporation. This paper explains the thermodynamic behavior of suc

Trifluoroacetic acid (TFA) presents unique handling challenges in evaporative workflows due to its volatility and corrosiveness. This document outlines optimized strategies to prevent sample loss a

This paper outlines key risks to sample integrity during centrifugal evaporation—overheating, cross-contamination, UV degradation, and compound loss—and the technologies Genevac employs to prev