Hull LyoStar® 4.0 R&D/Process Development Freeze Dryer

• You can never be too informed — LyoStar 4.0 provides more product and process information such as dried layer resistance, heat flow, mass transfer, and how different freezing protocols impact cake resistance
• Easily scalable — advanced, reliable, and scalable lyophilization technologies, along with Process Analytical Technology (PAT) tools, support smooth scale-up from process development through to manufacturing
• Unparalleled uniformity — superior shelf temperature mapping and rapid shelf freezing
• Ecologically sound — reduced carbon footprint with eco-friendlier refrigerant gas
• Cleanroom or isolator integrable — with optional 21 CFR Part 11 compatible software
• Decreases cycle development time and conserves valuable API
• Accessories and consumables for all your lyophilization needs — sample extractor, MVP probes, leveling feet, 21 CFR Part 11

To help you overcome the mounting challenges when scaling up your lyophilization processes, LyoConstellation™ lyophilizers are compatible with our state-of-the-art Line of Sight™ Lyophilization and Process Analytical Technologies (PAT) suite of scalable tools:

• LyoFlux® TDLAS — measure water vapor mass flow with accuracy during freeze-drying
• SMART™ Freeze Dryer Technology — get instant feedback on important product data including resistance, heat flow, and mass transfer
• TEMPRIS® Wireless Sensors — advanced wireless temperature monitoring for the highest quality product, on budget and on time
• ControLyo® Nucleation Technology — take control of your freeze-drying with cutting-edge nucleation technology for precise control of the freezing point

• Hull LyoStar® 4.0 R&D/Process Development Freeze Dryer
• Hull LyoStar 4.0 — Product Bulletin
• Basic Principles of Freeze Drying — Tech Note
• Technologies & PAT Tools to Overcome LyoChallenges — White Paper