Tempris: Wireless Product Temperature Measurement for Simpler, More Efficient, and Scalable Lyo Process Development

Product temperature measurement is the key to optimizing lyo cycles, working within the design space and conquering scale-up challenges. The most common method, using standard Type T Thermocouples, introduces many variables into the process and cannot be used in aseptic processing environments. 

Data and video to show how Tempris Wireless Sensors provide an easy way of implementing consistent, robust, repeatable product temperature measurement at all scales with many key advantages over standard PAT, will be presented. 

Leslie Mather is a lyophilization specialist with over 25 years of experience in pharmaceutical, diagnostic, and agricultural freeze-drying. After 24 years at Scientific Products, she founded LyoNavigation Services, LLC in 2023, offering freeze-drying training, and process and equipment consulting. She also serves as the U.S. sales representative for Tempris Wireless Sensors. At Scientific Products, she held technical, leadership, and educational roles including Director of R&D Lyophilizers, Product Specialist, and Technical Support and Training. She led the development of the company’s flagship R&D lyophilizer and commercialized three exclusive PAT tools. Leslie holds a B.S. from Cornell University. 

Anton Mangold, founder and CEO of Tempris GmbH (Holzkirchen, Germany), began as a banker and business economist, later expanding into electronics. He founded Tempris in 2002, inspired by automotive applications, and attracted the interest of a major German pharmaceutical company. A pioneer in wireless, battery-free temperature measurement, Tempris holds several patents and serves top pharmaceutical companies and CDMOs worldwide. Anton also co-founded GET Lyo Solutions, partnering with Gilyos and Explicat Pharma to deliver expertise in pharmaceutical freeze drying, QbD, and PAT strategies.