Analysts at Great Lakes Polymer Additives employed centrifugal evaporation to enhance safety and efficiency in competitive product de-formulation. Using the Genevac EZ-2 system, solvent removal fro
Archives: White Papers & Tech Notes
Basic Principles Of Freeze-Drying
Freeze-drying, or lyophilization, is a widely used dehydration technique that preserves material stability by removing water through sublimation under reduced pressure….
Advances in Sample Preparation for Metabolite Profiling
Metabolite profiling plays a crucial role in understanding drug metabolism and toxicity, but analytical accuracy can be compromised by errors introduced during sample preparation…
Integration for Medium to High Throughput HPLC Purification
High-throughput compound purification requires efficient sample tracking and solvent removal to maintain process integrity. This paper examines approaches for integrating preparative HPLC with evap
The Challenge Of Mixed Solvents
Mixtures containing both volatile and high-boiling-point solvents, such as methanol/DMSO systems, pose difficulties for controlled evaporation. This paper explains the thermodynamic behavior of suc
Surviving TFA
Trifluoroacetic acid (TFA) presents unique handling challenges in evaporative workflows due to its volatility and corrosiveness. This document outlines optimized strategies to prevent sample loss a
Sample Protection
This paper outlines key risks to sample integrity during centrifugal evaporation—overheating, cross-contamination, UV degradation, and compound loss—and the technologies Genevac employs to prev