By: Rob Darrington, Product Manager, Genevac Ltd., Stephen Pickrahn, Senior Scientist, International Flavors & Fragrances Inc. Introduction In the quest to find novel flavor ingredients from na
Archives: White Papers & Tech Notes
Development of an Enhanced Methodology & Technology for Safe, Rapid Freeze Drying of High Performance Liquid Chromatography Purification Fractions
By: Rob Darrington, Genevac Ltd., Ipswich, UK. Introduction Drying high performance liquid chromatography (HPLC) purification fractions, principally comprising water and acetonitrile, is a rou
Increasing Metabolite Recoveries in ADMET Studies of Animal Models Using a Centrifugal Evaporator
By: Sophie Mcdougall The effectiveness of ADME/Toxicology studies is, now more than ever, critical to the shortening the time-to-market of novel drugs. An ability to obtain rapidly accurate an
Sample Preparation for the Detection of Synthetic Analogues of Insulin in Human Serum
By: Dr Catrin Goebel Introduction The detection of the abuse of synthetic insulins by doping laboratories is likely to become a routine requirement. The World Anti-Doping Authority (WADA) code
The Importance of Reliable and Efficient Sample Preparation in the Development of a Novel Forensic Method To Detect Diclofenac Residues in Vultures and Livestock Animals
By: Ngaio Richards, Steve Lancaster, Sarah Hall, Karen Scott Introduction Diclofenac (Figure 1) is a non-steroidal anti- inflammatory drug (NSAID) that is extensively used to treat pain a
Integration for Medium to High Throughput HPLC Purification
By: Rob Darrington, Product Manager, Genevac Ltd., Paul de Fraine, Group Leader, Chem Tech Group Syngenta and Mike Jones, Group Leader, Scynexis Europe Ltd. Introduction In the modern purification
Automation Without Robotics: Elimination of Sample Transfer Steps To Optimize Yield and Data Quality in the Laboratory
By: Peter Bennett & Ian Whitehall Introduction Changing sample vessel format is an area of Discovery research that can cause problems: sample tracking, sample loss and robotic referen
Use of Centrifugal Evaporation in Polymer De-Formulation Chemistry
By: David Clayton, Stephen Knight Scientists working at the Great Lakes chemical company site in Manchester, UK have an interestingapproach to new product development.
Odour Reduction
By: SP Genevac Many solvent evaporators are routinely sited inside fume extraction hoods because residual solvent vapour, remaining in the chamber at the end of a run, can expose the operator to un
Evaluation of a New Technology Which Enables Large Volumes To Be Concentrated Directly Into a Small Vial for Use in Environmental Analysis
By: Dr. Raffaele Faita, Dr. Agostino Brunetta Introduction Leochimica Laboratories were founded in 1980, and are at the cutting edge of research into newmethods for environmental analysis. Wor