Penicillin, the first antibiotic, was discovered over 90 years ago and revolutionized medical potential. Before the advent of antibiotics, bacterial infections were a leading cause of death and the
Archives: White Papers & Tech Notes
PROTAC Technology for Novel Drug Discovery
Proteolysis Targeting Chimeras (PROTACs) were first conceptualized around 20 years ago and are transforming drug discovery. Before PROTACs, many disease-causing proteins were considered “undrugga
Eliminate HPLC Sample Preparation Bottlenecks with High Speed Evaporation and Lyophilization
High-performance liquid chromatography (HPLC) is a critical analytical technique for assessing oligonucleotide purity, yet conventional sample-preparation steps can create significant bottlenecks i
LGC, Biosearch Technologies Accelerate Probe and Primer Production to Enable COVID-19 Testing with the SP Genevac HT Series 3i Evaporator (Part 2)
As COVID-19 testing volumes expanded worldwide, maintaining consistency, throughput, and analytical confidence in oligonucleotide production became increasingly complex….
Using Parallel Evaporators to Escalate COVID-19 Test Kit Preparation (Part 1)
The emergence of COVID-19 generated an immediate global requirement for large quantities of high-performance oligonucleotides to support RT-qPCR diagnostic testing….
How the Implementation of eXalt™ for Evaporative Crystallisation Studies Improves Stability and Controlled Delivery in Drug Development
Controlled crystallization is essential in identifying and stabilizing polymorphic forms of active pharmaceutical ingredients….
Evaluation of Evaporative Sample Preparation Techniques for the Extraction of Drugs of Abuse from Urine Samples by Forensic Science Ireland
To enhance the sensitivity and reproducibility of LCMSMS drug screening in forensic casework, Forensic Science Ireland evaluated the Genevac EZ-2 system as an alternative to nitrogen blow-down evap
Odour Reduction
Residual solvent vapors can create hazardous and unpleasant odors upon completion of evaporation runs, even when condensers capture the bulk of vapors….
Evaluation of Evaporative Sample Preparation Techniques for Alcohol Markers and Drugs of Abuse in Hair Samples
Hair analysis provides a retrospective record of drug or alcohol use over extended periods, but sample volatility and contamination can compromise data reliability….
Evaluation of a New Technology Which Enables Large Volumes To Be Concentrated Directly Into a Small Vial for Use in Environmental Analysis
Leochimica Laboratories were founded in 1980, and are at the cutting edge of research into newmethods for environmental analysis. Working in a range of areas under the heading of Environmental An