evaporation Archives

Using Innovation to Enhance Revelation: SP Genevac EZ-2 Optimizes Screening for Novel Active Antimicrobial Compounds

By: Dr Jayneil Patel, Head of Metabolite Interactions & Dr Induka Abeysena, Portfolio Manager – SP Genevac Introduction Penicillin, the first antibiotic, was discovered over 90 years ago

Comparative Study of Two Different Centrifugal Evaporators in the Commercial Preparation of Dye Labelled Oligonucleotides.

By: K.S.Trevett and C.M.McKeen (Eurogentec S.A) The first system tested was a 15-year old design known as the SF-60 and supplied by Genevac Ltd, whilst the second system was a modern computer-

Improved Stability Drug Development

By: Ian Bailey, Biopharma Process Systems Background: Why there is a need for the Exalt™ application Polymorph screening is an important stage of drug

Developments in Laboratory Scale Lyophilisation for Purification Laboratories

By: Dr Induka Abeysena & Rob Darrington Introduction For many years lyophilisation, or freeze drying, has been used to dry samples in the laboratory. The technique is well researched

Tricks of the Trade for Removing High Boiling Point Solvents

By: SP Genevac What do we mean by “High Boiling Point”? Usually we mean things with a boiling point significantly higher than water.The graph below shows a range of solvents, with two w

Rapid, High Capacity Evaporation Solutions for Sophisticated Fractionation Processes

By: Rob Darrington, Product Manager, Genevac Ltd., Stephen Pickrahn, Senior Scientist, International Flavors & Fragrances Inc. Introduction In the quest to find novel flavor ingredients from na

Development of an Enhanced Methodology & Technology for Safe, Rapid Freeze Drying of High Performance Liquid Chromatography Purification Fractions

By: Rob Darrington, Genevac Ltd., Ipswich, UK. Introduction Drying high performance liquid chromatography (HPLC) purification fractions, principally comprising water and acetonitrile, is a rou

Increasing Metabolite Recoveries in ADMET Studies of Animal Models Using a Centrifugal Evaporator

By: Sophie Mcdougall The effectiveness of ADME/Toxicology studies is, now more than ever, critical to the shortening the time-to-market of novel drugs. An ability to obtain rapidly accurate an

Integration for Medium to High Throughput HPLC Purification

By: Rob Darrington, Product Manager, Genevac Ltd., Paul de Fraine, Group Leader, Chem Tech Group Syngenta and Mike Jones, Group Leader, Scynexis Europe Ltd. Introduction In the modern purification

Automation Without Robotics: Elimination of Sample Transfer Steps To Optimize Yield and Data Quality in the Laboratory

By: Peter Bennett & Ian Whitehall Introduction Changing sample vessel format is an area of Discovery research that can cause problems: sample tracking, sample loss and robotic referen

Use of Centrifugal Evaporation in Polymer De-Formulation Chemistry

By: David Clayton, Stephen Knight Scientists working at the Great Lakes chemical company site in Manchester, UK have an interestingapproach to new product development.

Odour Reduction

By: SP Genevac Many solvent evaporators are routinely sited inside fume extraction hoods because residual solvent vapour, remaining in the chamber at the end of a run, can expose the operator to un

Evaluation of a New Technology Which Enables Large Volumes To Be Concentrated Directly Into a Small Vial for Use in Environmental Analysis

By: Dr. Raffaele Faita, Dr. Agostino Brunetta Introduction Leochimica Laboratories were founded in 1980, and are at the cutting edge of research into newmethods for environmental analysis. Wor

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