Despite their advantages, DCS (dual chamber syringe) containers are not yet widely used, partly because no robust models yet exist that can accurately describe the freeze drying phenomena in these containers. One may attempt to leverage the existing heat and mass transfer models developed for vials. However, due to the different geometry of cartridges and vials, it is critical that significant modifications are made to these models before they can be applied. In this webinar, we report on the investigation of heat and mass transfer of a simple existing holder system for freeze drying in cartridges and dual chamber syringes, aimed at investigating whether vial model can be adopted for dual chamber syringes. Further, we will introduce a new holder design to improve the current heat and mass transfer properties. Novel and sophisticated monitoring pieces of apparatus are designed and incorporated to the new holder to facilitate data acquisition practices. Presented by Dr. Pouya Tavousi, PhD senior research scientist at the University of Connecticut
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