Freeze-drying is an effective approach to improve the storage stability of nanomedicines. The optimal freeze-drying process and lyoprotectants for three types of nanoparticles: solid lipid nanoparticles, polymeric nanoparticles, and liposomes were investigated. It was identified that various nanoparticle platforms have different behaviors in the freeze-drying process and require appropriate approaches to cope with. The impact of lyoprotectant selection and freeze-drying process on nanoparticle stability will be presented.
Presented by Dr. Xiuling Lu, Associate Professor of Pharmaceutics in the School of Pharmacy at the University of Connecticut
Speaker
Xiuling Lu, PhD
Associate Professor, University of Connecticut & Associate Director, CPPR
