Lyophilization and lyophilized products have been a foundational aspect of diagnostic kit manufacturing for decades. While cake lyophilization can address product stability, cold chain management, and material shipping weight issues, the formulation and formation of individual lyophilized beads offer developers and manufacturers with new dimensions in dose management, precision, and flexibility. Effectiveness and yields in lyobead formation are driven by volume precision and consistency in morphology. The BioJet™ dispensing technology from BioDot™ addresses each these critical aspects of lyobead production, all at high throughput. We will discuss the data and technology behind this novel approach. Brian Kirk has been with BioDot since 2001 and has spent that time designing, developing, and marketing high throughput manufacturing systems for many of the world’s leading diagnostic and life science companies. As a member of the original team who developed the patented FISHArrayTM technology and CellWriterTM workstation for cytogenetics, Brian now leads the Business Development team within BioDot where he leverages BioDot’s expertise in high throughput nanoliter and picoliter printing technologies to commercialize important tools for emerging life science markets.
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