LyoFlux® 200 TDLAS Sensors

Transform your lyophilization optimization workflow with the LyoFlux® 200 TDLAS (Tunable Diode Laser Absorption Spectroscopy) sensors, a near-infrared (NIR)-based PAT tool that is capable of accurately and sensitively monitoring water vapor mass flow during laboratory, pilot, and product scale freeze-drying cycles.

LyoFlux® is a registered trademark of Physical Sciences Inc., Andover, MA, USA. Image supplied by kind permission of Physical Sciences Inc.

Features & Benefits

  • Highly sensitive end-point determination for both primary and secondary drying
  • Continuous mass balance determination
  • Real-time calculation of average product temperature and resistance
  • Simple installation — the compact LyoFlux 200 can be installed in various sizes of developmental freeze dryers
  • Assessment of heat transfer coefficients (Kv) of vials — unlike other types of measurement sensors, the LyoFlux 200 TDLAS sensor is non-invasive, enabling you to determine product attributes without intervention, avoiding any compromise of product sterility in an aseptic environment
  • Simple scale-up — our LyoFlux 200 TDLAS technology can be applied from laboratory to production scale
  • Improve product quality — Quality by Design (QbD) approach enhances your understanding of product attributes and their impact on product quality
  • Maintains aseptic conditions — non-invasive measurement ensures product sterility

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