Hull LyoConstellation™ S10/S20/S30 Pilot Lyophilizers
Hull LyoConstellation™ S10/S20/S30 Pilot Lyophilizers
Hull LyoConstellation™ S10/S20/S30 Pilot Lyophilizers
If you need a lyophilizer that slots into your fill-finish workflow and is cleanroom ready, the Hull LyoConstellation™ pilot lyophilizers are here to help. With a comprehensive range of innovative technologies for your high-value products — including controlled ice nucleation, fluid condenser cooling, and large diameter vapor ports for high flow — we’ve done the hard work, so you don’t have to.
- Flexible — models include S10, S20, and S30 to ensure you get the lyophilizer you need
- Scalable — utilizes the same software and technology options as smaller systems
Overview
Our Hull LyoConstellation™ S10, S20 and S30 Development and Pilot Lyophilizers build on SP’s reputation as a pioneer of freeze-drying technologies. Designed to GMP standards and ready for full line integration, the LyoConstellation fits in where others cannot. And if time is not on your side, rest assured that our lyophilizers are configured to order — for faster than average market delivery.
And, to help you overcome the mounting challenges when scaling up your lyophilization processes, LyoConstellation lyophilizers are compatible with our state-of-the-art Line of Sight™ Process Analytical Technologies (PAT) suite of scalable tools:
- LyoFlux® TDLAS — measure water vapor mass flow with accuracy during freeze-drying
- SMART™ Freeze Dryer Technology — get instant feedback on important product data including resistance, heat flow, and mass transfer
- TEMPRIS® Wireless Sensors — advanced wireless temperature monitoring for the highest quality product, on budget and on time
- ControLyo® Nucleation Technology — take control of your freeze-drying with cutting-edge nucleation technology for precise control of the freezing point
Features & Benefits
- Taking you from start to finish — ideal for cycle development and scale-up to stability, pilot, and clinical batch production, through full aseptic production
- Technologies that ensure quality — full suite of PAT tools and technologies enables Line of Sight approach in cycle development and scale-up for simplified technology transfer, assuring product safety and quality in production
- Validation made easy — validation ports in chamber and condenser as standard, with full documentation package and support available
- Accurate end points — Pirani gauge and capacitance manometer as standard
- Built for demanding lyophilization needs — each of our units accommodate vials up to 30 mL and can hold 100 mTorr while shelves are at +40⁰C fully loaded
- Full Steam in Place (SIP) & Clean in Place (CIP) execution, with manual/H2O2 option
- Isolator ready with auto locking doors
